DNA for Windows!
A small but powerful DNA sequence editing and analysis program for
Windows
95/98/NT/ME/2000/XP
Current shareware version: 2.2.1
Current version for registered users: 2.5.1
NEW - Registered users
should have recently received v. 2.5.1. If
you have registered and haven't received the update, please contact me.
NEW - Trial edition of
registered version available - see below.
Note: I can now accept credit card payments
through PayPal. Just click
on the button below & follow the instructions - you will be emailed
the registered version and all subsequent updates.
Introduction
DNA for Windows is a compact, easy to use DNA analysis program, ideal
for
small-scale sequencing projects. It is particularly suited to
working
with chromatogram files from ABI machines, and is one of the few
programs
able to edit as well as view these files. The program has
powerful
DNA translation and restriction enzyme analysis facilities, and works
with
external programs to produce multiple alignments and contigs with ease.
Figure 1. Main application with list of sequences (top
window) text-based analysis (middle window) and graphical analysis
(bottom
window)
General Features:
Three-window
view
- maximise one or view all three, making navigation easy.
Loads FASTA
format
sequences
and extracts sequences from text files.
Easy
manipulation
of sequences - removal of 'junk' text, reverse, complement, trim,
etc.
Restriction
enzyme
analysis - custom groups of enzymes, only show enzymes that cut a
certainnumber of times.
Translation
of
DNA to protein - Choice of 1-, 3- or 6-frame; can calculate mass
of selected protein.
Easy multiple
sequence alignment using interface to CLUSTALW program.
Manual
multiple
alignment - e.g. for 'tweaking' alignments.
Calculation
of
codon usage.
Automatic
contig
assembly - using interface to CAP program.
Dot-Plot
analysis
of 1 or 2 sequences.
ABI Chromatogram Manipulation:
Reads AND
WRITES
ABI chromatogram files.
Views
chromatogram,
with scalable X- and Y- axes (see figure 2), custom colours,
etc.
Easy editing
of
base calls, with a single mouse click.
Automatic
alignment
with a second chromatogram - to quickly check base calls, or assemble
contig.
Highly
configurable
printing of chromatogram - auto scaling of peak heights, line
thickness,
number of rows, etc.
Figure 2. Chromatogram view window.
Download Files
View the README file for DNA for Windows
Download a fully
functional
evaluation version (780 KB)
If you wish to perform multiple alignments you will also need to
download and install ClustalW from:
ftp://ftp.ebi.ac.uk/pub/software/dos/clustalw/clustalw1.83.XP.zip
NEW - A trial edition of
registered version is available - This is identical to the registered
version but INTRODUCES RANDOM ERRORS INTO YOUR SEQUENCES, and is for
testing purposes only. Download trial
here.
If you find the program useful, don't forget to register - you will
receive
the latest version which already has a number of significant
improvements
over the evaluation version.
Contact the Author
Please try the program and let me know what you think - if you don't
tell
me what's wrong with it I can't improve it!
David
Dixon
Department of Biological Sciences, University
of Durham,
South Road, Durham.
DH1 3LE
UK
Research
group homepage.